Smug1^tm1.1Hln
Targeted Allele Detail

Summary

• Symbol: Smug1^tm1.1Hln
• Name: single-strand selective monofunctional uracil DNA glycosylase; targeted mutation 1.1, Hilde Nilsen
• MGI ID: MGI:6432316
• Synonyms: Smug1^tm1lHn
• Gene: Smug1 Location: Chr15:103061717-103075519 bp, - strand Genetic Position: Chr15, 58.2 cM
• Alliance: Smug1^tm1.1Hln page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253596
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 1 and 2 were flanked with loxP sites. Exons 1 and 2 were deleted via Cre-mediated recombination in the germline. (J:253596)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smug1 Mutation: 13 strains or lines available

References

• Original: J:253596 Alsoe L, et al., Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1. Sci Rep. 2017 Aug 3;7(1):7199
• All: 2 reference(s)