About   Help   FAQ
Cfap69em1Fzh
Endonuclease-mediated Allele Detail
Summary
Symbol: Cfap69em1Fzh
Name: cilia and flagella associated protein 69; endonuclease-mediated mutation 1, Feng Zhang
MGI ID: MGI:6431857
Gene: Cfap69  Location: Chr5:5629284-5714232 bp, - strand  Genetic Position: Chr5, 3.07 cM
Alliance: Cfap69em1Fzh page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR/Cas9 technology deleted exons 2-4, resulting in a frameshift mutation. (J:288345)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cfap69 Mutation:  57 strains or lines available
References
Original:  J:288345 He X, et al., Novel homozygous CFAP69 mutations in humans and mice cause severe asthenoteratospermia with multiple morphological abnormalities of the sperm flagella. J Med Genet. 2019 Feb;56(2):96-103
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory