Gt(ROSA)26Sor^{tm5(CAG-Nod2)Mrl}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm5(CAG-Nod2)Mrl}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 5, Merck Research Laboratory
• MGI ID: MGI:6431836
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm5(CAG-Nod2)Mrl} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Constitutively active, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The targeting construct inserted a CAG promoter cassette, loxP-flanked transcription termination cassette (STOP) containing a combination of polyadenylation signal, the Nod2 open reading frame together with a Kozak sequence (GCCACC), the human growth hormone polyadenylation signal, and an additional polyadenylation signal. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 1 reference(s)