Cfap43^em1.1Gos
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cfap43^em1.1Gos
• Name: cilia and flagella associated protein 43; endonuclease-mediated mutation 1.1, Achim Gossler
• MGI ID: MGI:6431400
• Synonyms: Cfap43^loxP
• Gene: Cfap43 Location: Chr19:47723706-47825893 bp, - strand Genetic Position: Chr19, 40.41 cM, cytoband D2
• Alliance: Cfap43^em1.1Gos page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology flanked exon 3 with loxP sites and inserted a FRT-flanked neomycin resistance cassette upstream of exon 3. Flp-mediated recombination removed the selection cassette. (J:286555)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cfap43 Mutation: 71 strains or lines available

References

• Original: J:286555 Rachev E, et al., CFAP43 modulates ciliary beating in mouse and Xenopus. Dev Biol. 2020 Mar 15;459(2):109-125
• All: 1 reference(s)