Adgrf1^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Adgrf1^tm1Smoc
• Name: adhesion G protein-coupled receptor F1; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6430805
• Gene: Adgrf1 Location: Chr17:43581220-43635628 bp, + strand Genetic Position: Chr17, 19.71 cM
• Alliance: Adgrf1^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279107
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 11-13 were replaced by a pGK-Neomycin selection cassette. (J:279107)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgrf1 Mutation: 46 strains or lines available

References

• Original: J:279107 Ma B, et al., Gpr110 deficiency decelerates carcinogen-induced hepatocarcinogenesis via activation of the IL-6/STAT3 pathway. Am J Cancer Res. 2017;7(3):433-447
• All: 2 reference(s)