Il1b^{tm3(IL1B)Smoc}
Targeted Allele Detail

Summary

• Symbol: Il1b^{tm3(IL1B)Smoc}
• Name: interleukin 1 beta; targeted mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:6430639
• Synonyms: Il1b^{tm3(hIL1B)Smoc}
• Gene: Il1b Location: Chr2:129206490-129213059 bp, - strand Genetic Position: Chr2, 62.97 cM, cytoband F
• Alliance: Il1b^{tm3(IL1B)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Il1b^{tm3(IL1B)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IL1B (3553)

  Il1b	(MGI:96543)

• Mutation details: CRISPR/Cas9 genome editing technology was used to insert the human IL1B gene into in place of the endogenous mouse gene. (J:238766)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il1b Mutation: 23 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)