Six1^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Six1^em1Smoc
• Name: sine oculis-related homeobox 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6430636
• Gene: Six1 Location: Chr12:73088601-73093486 bp, - strand Genetic Position: Chr12, 30.34 cM
• Alliance: Six1^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to target exon 1 of the gene. (J:258624)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Six1 Mutation: 19 strains or lines available

References

• Original: J:258624 Li L, et al., Transcriptional Regulation of the Warburg Effect in Cancer by SIX1. Cancer Cell. 2018 Mar 12;33(3):368-385.e7
• All: 1 reference(s)