Del(16Dgcr2-Hira)2Tac
Targeted Allele Detail

Summary

• Symbol: Del(16Dgcr2-Hira)2Tac
• Name: deletion, Chr 16, Taconic 2
• MGI ID: MGI:6430609
• Synonyms: Del(16Dgcr2-Hira)1Tac, Del2Tac, Df(h22q11)
• Gene: Del(16Dgcr2-Hira)2Tac Location: unknown

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion, Intragenic deletion
• Mutation details: The deletion was generated by cre-mediated recombination of a loxp site inserted upstream of Dgcr2 and a loxP site inserted downstream of Hira. (J:288167)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(16Dgcr2-Hira)2Tac Mutation: 0 strains or lines available

References

• Original: J:288167 Didriksen M, et al., Persistent Gating Deficit and Increased Sensitivity to NMDA Receptor Antagonism After Puberty in a New Mouse Model of the Human 22q11.2 Microdeletion Syndrome: A Study in Male Mice. J Psychiatry Neurosci. 2017;42(1):48-58
• All: 8 reference(s)