Eqtn^tm1Ktos
Targeted Allele Detail

Summary

• Symbol: Eqtn^tm1Ktos
• Name: equatorin, sperm acrosome associated; targeted mutation 1, Kiyotaka Toshimori
• MGI ID: MGI:6430563
• Gene: Eqtn Location: Chr4:94795504-94817080 bp, - strand Genetic Position: Chr4, 43.34 cM, cytoband C5
• Alliance: Eqtn^tm1Ktos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:285739
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exon 1-5. (J:285739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Eqtn Mutation: 23 strains or lines available

References

• Original: J:285739 Ito C, et al., Deletion of Eqtn in mice reduces male fertility and sperm-egg adhesion. Reproduction. 2018 Dec;156(6):579-590
• All: 1 reference(s)