Tg(TcraTcrb)7Mjb
Transgene Detail

Summary

• Symbol: Tg(TcraTcrb)7Mjb
• Name: transgene insertion 7, Michael J Bevan
• MGI ID: MGI:6430441
• Synonyms: OT-3
• Transgene: Tg(TcraTcrb)7Mjb Location: unknown
• Alliance: Tg(TcraTcrb)7Mjb page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• The transgene contains a receptor rearrangement recognizing ovalbumin 257-264 known as clone 7. (J:191273)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:191273 Enouz S, et al., Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection. J Exp Med. 2012 Sep 24;209(10):1769-79
• All: 6 reference(s)