Hdc^em1Luval
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hdc^em1Luval
• Name: histidine decarboxylase; endonuclease-mediated mutation 1, Luc Vallieres
• MGI ID: MGI:6430439
• Synonyms: Hdc-fl, Hdc^fl
• Gene: Hdc Location: Chr2:126435587-126461219 bp, - strand Genetic Position: Chr2, 61.76 cM, cytoband E5-G
• Alliance: Hdc^em1Luval page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: CRISPR-targeting insertion of loxP sequences into introns 7 and 9, allowing to delete exons 8 and 9 in the presence of cre. (J:288146)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hdc Mutation: 52 strains or lines available

References

• Original: J:288146 Morin F, et al., Direct Data Submission for Hdc-fl. MGI Direct Data Submission. 2020
• All: 2 reference(s)