Ambra1^em1Thore
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ambra1^em1Thore
• Name: autophagy/beclin 1 regulator 1; endonuclease-mediated mutation 1, Wallace Thoreson
• MGI ID: MGI:6423701
• Gene: Ambra1 Location: Chr2:91560479-91749194 bp, + strand Genetic Position: Chr2, 50.63 cM
• Alliance: Ambra1^em1Thore page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 4 was floxed. (J:263636)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ambra1 Mutation: 118 strains or lines available

References

• Original: J:263636 Quadros RM, et al., Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins. Genome Biol. 2017 May 17;18(1):92
• All: 3 reference(s)