Meiob^tm1.1Jw
Targeted Allele Detail

Summary

• Symbol: Meiob^tm1.1Jw
• Name: meiosis specific with OB domains; targeted mutation 1.1, Jeremy Wang
• MGI ID: MGI:6423285
• Gene: Meiob Location: Chr17:25023275-25058762 bp, + strand Genetic Position: Chr17, 12.53 cM, cytoband A3.3
• Alliance: Meiob^tm1.1Jw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:204663
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette replaced exons 6 through 10. Cre-mediated recombination removed the selection cassette. (J:204663)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meiob Mutation: 28 strains or lines available

References

• Original: J:204663 Luo M, et al., MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination. Nat Commun. 2013;4:2788
• All: 2 reference(s)