Rnu11^tm1Ttg
Targeted Allele Detail

Summary

• Symbol: Rnu11^tm1Ttg
• Name: U11 small nuclear RNA; targeted mutation 1, Taniguchi Tadatsugu
• MGI ID: MGI:6423269
• Gene: Rnu11 Location: Chr4:131997390-131997497 bp, - strand Genetic Position: Chr4, 65.08 cM
• Alliance: Rnu11^tm1Ttg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282326
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• A 613 bp region containing the entire gene was flanked by loxP sites. (J:282326)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnu11 Mutation: 1 strain or line available

Notes

ES cell line = HK3i (C57BL/6NJcl)

References

• Original: J:282326 Negishi H, et al., Identification of U11snRNA as an endogenous agonist of TLR7-mediated immune pathogenesis. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23653-23661
• All: 1 reference(s)