Mdga2^tm1Fuma
Targeted Allele Detail

Summary

• Symbol: Mdga2^tm1Fuma
• Name: MAM domain containing glycosylphosphatidylinositol anchor 2; targeted mutation 1, Fumio Matsuzaki
• MGI ID: MGI:6423146
• Gene: Mdga2 Location: Chr12:66512834-67269323 bp, - strand Genetic Position: Chr12, 27.63 cM
• Alliance: Mdga2^tm1Fuma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:253274
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• he coding sequence in the exon was replaced by a LacZ-pA-PGK-Neo-pA cassette. (J:253274)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mdga2 Mutation: 77 strains or lines available

References

• Original: J:253274 Connor SA, et al., Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2. Neuron. 2016 Sep 7;91(5):1052-1068
• All: 2 reference(s)