Srcin1^tm1.1Pdfi
Targeted Allele Detail

Summary

• Symbol: Srcin1^tm1.1Pdfi
• Name: SRC kinase signaling inhibitor 1; targeted mutation 1.1, Paola Defilippi
• MGI ID: MGI:6423109
• Gene: Srcin1 Location: Chr11:97400166-97466059 bp, - strand Genetic Position: Chr11, 61.0 cM, cytoband D
• Alliance: Srcin1^tm1.1Pdfi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:285611
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 5. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 11. Flp-mediated recombination removed the selection cassette and left exons 5 through 11 floxed. (J:285611)

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Srcin1 Mutation: 52 strains or lines available

References

• Original: J:285611 Russo I, et al., p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits. Cereb Cortex. 2019 Jan 1;29(1):91-105
• All: 1 reference(s)