Crybg3^nct
Spontaneous Allele Detail

Summary

• Symbol: Crybg3^nct
• Name: beta-gamma crystallin domain containing 3; Nakano cataract
• MGI ID: MGI:6416568
• Gene: Crybg3 Location: Chr16:59312451-59421410 bp, - strand Genetic Position: Chr16, 34.83 cM
• Alliance: Crybg3^nct page

Mutation origin

• Strain of Origin: C.Cg-Cpox^nct/JmsRbrc

Mutation description

• Allele Type: Spontaneous (Not Specified)
• Mutation: Single point mutation
• Mutation details: A spontaneous T-to-C mutation (A-to-G on negative gene strand) changes conserved asparagine codon 744 to aspartic acid (p.N744D). This mutation is found in C.Cg-Cpox^nct/JmsRbrc mice. (J:196645)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crybg3 Mutation: 85 strains or lines available

References

• Original: J:196645 Mori M, et al., Hereditary cataract of the Nakano mouse: Involvement of a hypomorphic mutation in the coproporphyrinogen oxidase gene. Exp Eye Res. 2013 Apr 28;112C:45-50
• All: 2 reference(s)