Tg(Prop1-cre)1Rsd
Transgene Detail

Summary

• Symbol: Tg(Prop1-cre)1Rsd
• Name: transgene insertion 1, Michael G Rosenfeld
• MGI ID: MGI:6415528
• Synonyms: Prop1-Cre
• Transgene: Tg(Prop1-cre)1Rsd Location: unknown
• Alliance: Tg(Prop1-cre)1Rsd page

Transgene origin

• Strain of Origin: (BALB/c x C57BL/6)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Prop1-cre)1Rsd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prop1 (MGI:109330)

• Mutation details: A 2181 bp HindIII genomic DNA fragment incorporating the mouse Prop1 promoter and enhancer regions (extending from 967 bp upstream of the coding sequence to 59 bases into the second exon) drives expression of cre recombinase with a synthetic poly A tail. The mutation was created in CB6F1 (BALB/c x C57BL/6) embryos. (J:287133)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prop1 (mouse) Summary of all recombinase alleles driven by Prop1. Comparative matrix view of recombinase activities Alliance mouse Prop1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:287133 Zhu X, et al., Notch-Dependent Pituitary SOX2(+) Stem Cells Exhibit a Timed Functional Extinction in Regulation of the Postnatal Gland. Stem Cell Reports. 2015 Dec 8;5(6):1196-1209
• All: 2 reference(s)