Snta1^tm1.1Pg
Targeted Allele Detail

Summary

• Symbol: Snta1^tm1.1Pg
• Name: syntrophin, acidic 1; targeted mutation 1.1, PolyGene AG
• MGI ID: MGI:6414571
• Synonyms: Snta1 fl
• Gene: Snta1 Location: Chr2:154218234-154250004 bp, - strand Genetic Position: Chr2, 76.52 cM
• Alliance: Snta1^tm1.1Pg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:286963
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP- and FRT-flanked neomycin resistance cassette was inserted into the 5' UTR of exon 1. An additional loxP site was inserted into intron 1. Flp-mediated recombination removed the selection cassette and left 0.7 kb of exon 1 floxed. (J:286963)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Snta1 Mutation: 35 strains or lines available

References

• Original: J:286963 Rougier JS, et al., A Distinct Pool of Na(v)1.5 Channels at the Lateral Membrane of Murine Ventricular Cardiomyocytes. Front Physiol. 2019;10:834
• All: 1 reference(s)