Del(1Cd244a-Slamf6)1Vei
Targeted Allele Detail

Summary

• Symbol: Del(1Cd244a-Slamf6)1Vei
• Name: deletion, Chr 1, Andre Veillette
• MGI ID: MGI:6407413
• Synonyms: Del1Vei, delta Slam
• Gene: Del(1Cd244a-Slamf6)1Vei Location: unknown Genetic Position: Chr1, Syntenic

Mutation origin

• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(1Cd244a-Slamf6)1Vei involves 22 genes/genome features (2410084L01Rik, n-THatg1, Gm35200 ...) View all
• Mutation details: Cre-mediated recombination between a single loxP site and neomycin resistance cassette inserted into intron 1 of Cd244a (Slamf4) and a single loxP site and hygromycin resistance cassette inserted into intron 7 of Slamf6 deleted the intervening sequence spanning the Slamf protein family. (J:237231)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(1Cd244a-Slamf6)1Vei Mutation: 0 strains or lines available

References

• Original: J:237231 Guo H, et al., Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016 Sep 19;213(10):2187-207
• All: 4 reference(s)