Gpr84^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gpr84^tm1Dgen
• Name: G protein-coupled receptor 84; targeted mutation 1, Deltagen
• MGI ID: MGI:6406877
• Gene: Gpr84 Location: Chr15:103216662-103219039 bp, - strand Genetic Position: Chr15, 58.88 cM
• Alliance: Gpr84^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222553
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Targeting replaced 257 bp of coding sequence with an IRESLacZpoly(A) expression cassette and a positive selection cassette that contains the neomycin phosphotransferase gene driven by the PGK promoter (Neo). The insertion of the LacZ gene cassette introduces a premature translational stop signal that deletes the first three predicted transmembrane domain sequences. (J:222553)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr84 Mutation: 33 strains or lines available

References

• Original: J:222553 Nicol LS, et al., The Role of G-Protein Receptor 84 in Experimental Neuropathic Pain. J Neurosci. 2015 Jun 10;35(23):8959-69
• All: 4 reference(s)