Itpr1^m1Yzcm
Chemically induced Allele Detail

Summary

• Symbol: Itpr1^m1Yzcm
• Name: inositol 1,4,5-trisphosphate receptor 1; mutation 1, Yangzhou University
• MGI ID: MGI:6405752
• Synonyms: Ip3r1^C1976Y
• Gene: Itpr1 Location: Chr6:108190057-108528070 bp, + strand Genetic Position: Chr6, 49.74 cM
• Alliance: Itpr1^m1Yzcm page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: ENU mutagenesis induced a G to A point mutation (G5927A) that results in the amino acid substitution of tyrosine for cysteine at position 1976. (J:286002)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Itpr1 Mutation: 185 strains or lines available

References

• Original: J:286002 Chen B, et al., A C1976Y missense mutation in the mouse Ip3r1 gene leads to short-term mydriasis and unfolded protein response in the iris constrictor muscles. Exp Anim. 2020 Jan 29;69(1):45-53
• All: 1 reference(s)