Myo16^em3Hhtg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Myo16^em3Hhtg
• Name: myosin XVI; endonuclease-mediated mutation 3, Irm Hermans-Borgmeyer
• MGI ID: MGI:6405673
• Synonyms: Myo16^{L line}
• Gene: Myo16 Location: Chr8:10203911-10684742 bp, + strand Genetic Position: Chr8, 4.77 cM
• Alliance: Myo16^em3Hhtg page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 269 bp comprising exon 3. (J:286005)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myo16 Mutation: 94 strains or lines available

References

• Original: J:286005 Roesler MK, et al., Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization. Front Cell Neurosci. 2019;13:330
• All: 1 reference(s)