Pilrb1^em1Dvst
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pilrb1^em1Dvst
• Name: paired immunoglobin-like type 2 receptor beta 1; endonuclease-mediated mutation 1, Dietmar Vestweber
• MGI ID: MGI:6405409
• Gene: Pilrb1 Location: Chr5:137850409-137856368 bp, - strand Genetic Position: Chr5, 76.82 cM
• Alliance: Pilrb1^em1Dvst page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting removed 3.1 kDa between intron 2 and intron 4. RT-PCR confirmed the absence of transcript expression with normal expression of Pilrb2. (J:286045)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pilrb1 Mutation: 9 strains or lines available

References

• Original: J:286045 Li YT, et al., Blood flow guides sequential support of neutrophil arrest and diapedesis by PILR-beta1 and PILR-alpha. Elife. 2019 Aug 6;8:e47642
• All: 1 reference(s)