Cdc40^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdc40^em1(IMPC)Bay
• Name: cell division cycle 40; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:6404505
• Gene: Cdc40 Location: Chr10:40707617-40759139 bp, - strand Genetic Position: Chr10, 22.06 cM, cytoband B1
• Alliance: Cdc40^em1(IMPC)Bay page
• IMPC: Cdc40 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and guides with spacer sequences ACAAAGAACACTATGGTTCT, ACACACGGTTCAGTGTAATC, CGGGGCTGACTGGCCTATTT, and CTTTATAGGTGAGCATGAGA that targeted exon(s) ENSMUSE00000299423.4. This resulted in deletion(s) of 397 bp (location: Chr10:40733399-40733795; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cdc40 Mutation: 36 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 4 reference(s)