Aifm2^em1Hsul
Endonuclease-mediated Allele Detail

Summary

• Symbol: Aifm2^em1Hsul
• Name: apoptosis-inducing factor, mitochondrion-associated 2; endonuclease-mediated mutation 1, Hei Sul
• MGI ID: MGI:6404479
• Gene: Aifm2 Location: Chr10:61551042-61575039 bp, + strand Genetic Position: Chr10, 32.27 cM
• Alliance: Aifm2^em1Hsul page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 22 bp from the third coding exon. (J:286182)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aifm2 Mutation: 21 strains or lines available

References

• Original: J:286182 Nguyen HP, et al., Aifm2, a NADH Oxidase, Supports Robust Glycolysis and Is Required for Cold- and Diet-Induced Thermogenesis. Mol Cell. 2020 Feb 6;77(3):600-617.e4
• All: 1 reference(s)