Slc38a4^em2Smtb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc38a4^em2Smtb
• Name: solute carrier family 38, member 4; endonuclease-mediated mutation 2, Shogo Matoba
• MGI ID: MGI:6403487
• Synonyms: Slc38a4^#12-B
• Gene: Slc38a4 Location: Chr15:96892701-96953837 bp, - strand Genetic Position: Chr15, 52.77 cM
• Alliance: Slc38a4^em2Smtb page

Mutation origin

• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of the first 10 exons deleted 23,146bp (95997025 to 97020173; mm10). (J:280426)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc38a4 Mutation: 116 strains or lines available

References

• Original: J:280426 Matoba S, et al., Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):21047-21053
• All: 1 reference(s)