Sod1tm1.1(SOD1)Emcf
Targeted Allele Detail
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Symbol: |
Sod1tm1.1(SOD1)Emcf |
Name: |
superoxide dismutase 1, soluble; targeted mutation 1, Elizabeth MC Fisher |
MGI ID: |
MGI:6403195 |
Synonyms: |
SOD1-3-A10-Flp excised |
Gene: |
Sod1 Location: Chr16:90017650-90023221 bp, + strand Genetic Position: Chr16, 51.56 cM, cytoband B5-C3
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Alliance: |
Sod1tm1.1(SOD1)Emcf page
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Allele Type: |
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Targeted (Conditional ready, Humanized sequence, Null/knockout) |
Mutation: |
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Insertion
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Mutation details: The mouse sequence is replaced with the human sequence that has a floxed duplication of exons 4 and 5. An FRT-flanked selection cassette was inserted downstream of the first human exon 5. Flp-mediated recombination removed the selection cassette and left the first set of human exon 4 and 5 floxed.
(J:342505)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Sod1 Mutation: |
39 strains or lines available
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Original: |
J:342505 Devoy A, et al., Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models. iScience. 2021 Dec 17;24(12):103463 |
All: |
2 reference(s) |
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