Clec5a^tm1Mbor
Targeted Allele Detail

Summary

• Symbol: Clec5a^tm1Mbor
• Name: C-type lectin domain family 5, member a; targeted mutation 1, Michael T Borchers
• MGI ID: MGI:6402921
• Synonyms: Clec5a^-
• Gene: Clec5a Location: Chr6:40551832-40562739 bp, - strand Genetic Position: Chr6, 18.82 cM, cytoband B2
• Alliance: Clec5a^tm1Mbor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:286240
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• A targeting vector containing a neomycin resistance cassette was used to replace exon 2. (J:286240)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Clec5a Mutation: 18 strains or lines available

References

• Original: J:286240 Wortham BW, et al., CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies. J Immunol. 2016 Apr 15;196(8):3227-31
• All: 1 reference(s)