Thbs4^m1H
Chemically induced Allele Detail

Summary

• Symbol: Thbs4^m1H
• Name: thrombospondin 4; mutation 1, Harwell
• MGI ID: MGI:6402824
• Synonyms: Thbs4^T449A
• Gene: Thbs4 Location: Chr13:92888098-92931326 bp, - strand Genetic Position: Chr13, 47.75 cM
• Alliance: Thbs4^m1H page

Mutation origin

• Strain of Origin: (C3H/HeH x C57BL/6J)F1

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis caused an A to G mutation at base 1490 (ENSMUST00000022213.7), resulting in a missense amino acid change at residue 449 of threonine (T) to alanine (A) (p.T449A). (J:251771)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thbs4 Mutation: 69 strains or lines available

References

• Original: J:251771 Moir L, et al., Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety. Mol Metab. 2017 Nov;6(11):1419-1428
• All: 1 reference(s)