Dmd^em2Eno
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dmd^em2Eno
• Name: dystrophin, muscular dystrophy; endonuclease-mediated mutation 2, Eric N Olson
• MGI ID: MGI:6393599
• Synonyms: WT-Dmd-Luc
• Gene: Dmd Location: ChrX:81992476-84249747 bp, + strand Genetic Position: ChrX, 38.38 cM, cytoband C
• Alliance: Dmd^em2Eno page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• CRISPR targeting introduced a 2A sequence and the luciferase reporter gene downstream of exon 79. (J:281379)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dmd Mutation: 167 strains or lines available

References

• Original: J:281379 Amoasii L, et al., In vivo non-invasive monitoring of dystrophin correction in a new Duchenne muscular dystrophy reporter mouse. Nat Commun. 2019 Oct 4;10(1):4537
• All: 1 reference(s)