Cyp27a1^tm1.1Dpm
Targeted Allele Detail

Summary

• Symbol: Cyp27a1^tm1.1Dpm
• Name: cytochrome P450, family 27, subfamily a, polypeptide 1; targeted mutation 1.1, Donald McDonnell
• MGI ID: MGI:6393263
• Synonyms: Cy27a1^f
• Gene: Cyp27a1 Location: Chr1:74752733-74777051 bp, + strand Genetic Position: Chr1, 38.54 cM, cytoband C3
• Alliance: Cyp27a1^tm1.1Dpm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector was constructed to insert a loxP site upstream of exon 2 and a FRT-flanked neomycin selection cassette and another loxP site downstream of exon 2. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 2 floxed. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cyp27a1 Mutation: 30 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)