Kcnk9^em1Hyyg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kcnk9^em1Hyyg
• Name: potassium channel, subfamily K, member 9; endonuclease-mediated mutation 1, Huaiyu Yang
• MGI ID: MGI:6392167
• Synonyms: Kcnk9^delta
• Gene: Kcnk9 Location: Chr15:72372938-72418189 bp, - strand Genetic Position: Chr15, 33.46 cM
• Alliance: Kcnk9^em1Hyyg page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting produced a 241-bp deletion in exon 1. (J:283506)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnk9 Mutation: 13 strains or lines available

References

• Original: J:283506 Liao P, et al., Selective activation of TWIK-related acid-sensitive K(+) 3 subunit-containing channels is analgesic in rodent models. Sci Transl Med. 2019 Nov 20;11(519)
• All: 2 reference(s)