Surf4^em1Dgi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Surf4^em1Dgi
• Name: surfeit gene 4; endonuclease-mediated mutation 1, David Ginsburg
• MGI ID: MGI:6392162
• Gene: Surf4 Location: Chr2:26810053-26823793 bp, - strand Genetic Position: Chr2, 19.1 cM
• Alliance: Surf4^em1Dgi page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 targeting exon 2 produced a single base pair deletion that results in a premature termination. (J:284050)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Surf4 Mutation: 16 strains or lines available

References

• Original: J:284050 Emmer BT, et al., Murine Surf4 is essential for early embryonic development. PLoS One. 2020;15(1):e0227450
• All: 1 reference(s)