Runx1^tm3.1Glac
Targeted Allele Detail

Summary

• Symbol: Runx1^tm3.1Glac
• Name: runt related transcription factor 1; targeted mutation 3.1, Georges Lacaud
• MGI ID: MGI:6392015
• Synonyms: Runx1b::rfp
• Gene: Runx1 Location: Chr16:92398354-92622962 bp, - strand Genetic Position: Chr16, 53.7 cM
• Alliance: Runx1^tm3.1Glac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237528
• Parent Cell Line: BK4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region of exon 3 was replaced with RFP. A floxed neo cassette used for selection purposes was removed by cre mediated recombination. (J:237528)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Runx1 Mutation: 34 strains or lines available

References

• Original: J:237528 Lilly AJ, et al., Interplay between SOX7 and RUNX1 regulates hemogenic endothelial fate in the yolk sac. Development. 2016 Dec 01;143(23):4341-4351
• All: 2 reference(s)