Mapk3^em1Mhsi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mapk3^em1Mhsi
• Name: mitogen-activated protein kinase 3; endonuclease-mediated mutation 1, Michael Simons
• MGI ID: MGI:6389781
• Synonyms: Erk1^Fl
• Gene: Mapk3 Location: Chr7:126358798-126364988 bp, + strand Genetic Position: Chr7, 69.25 cM
• Alliance: Mapk3^em1Mhsi page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 genome editing is used to introduce loxP sites surrounding exons 3-8. (J:283746)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mapk3 Mutation: 27 strains or lines available

References

• Original: J:283746 Ricard N, et al., Isoform-Specific Roles of ERK1 and ERK2 in Arteriogenesis. Cells. 2019 Dec 21;9(1):38
• All: 1 reference(s)