Metrn^tm1.1Kong
Targeted Allele Detail

Summary

• Symbol: Metrn^tm1.1Kong
• Name: meteorin, glial cell differentiation regulator; targeted mutation 1.1, Young-Yun Kong
• MGI ID: MGI:6388733
• Synonyms: Meteorin^-
• Gene: Metrn Location: Chr17:26013545-26016019 bp, - strand Genetic Position: Chr17, 12.89 cM, cytoband A3.3
• Alliance: Metrn^tm1.1Kong page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283312
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 1 and its 3' downstream sequence were substituted with an IRES-LacZ-Puro cassette with the puromycin resistance gene flanked by FRT sites. Flp-mediated recombination removed the puromycin resistance cassette. (J:283312)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Metrn Mutation: 16 strains or lines available

References

• Original: J:283312 Kim YY, et al., Meteorin regulates mesendoderm development by enhancing nodal expression. PLoS One. 2014;9(2):e88811
• All: 1 reference(s)