Nanos2^em2(cre)Jahe
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nanos2^em2(cre)Jahe
• Name: nanos C2HC-type zinc finger 2; endonuclease-mediated mutation 2, Jason Heaney
• MGI ID: MGI:6388705
• Synonyms: Nanos2^Cre
• Gene: Nanos2 Location: Chr7:18721449-18722887 bp, + strand Genetic Position: Chr7, 9.45 cM
• Alliance: Nanos2^em2(cre)Jahe page

Mutation origin

• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout, Recombinase)
• Mutations: Insertion, Intragenic deletion
• Nanos2^em2(cre)Jahe expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nanos2 (MGI:2676627)

• The cre recombinase gene inserted 21 bp from the start replacing the rest of the coding region. (J:305432)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nanos2 (mouse) Summary of all recombinase alleles driven by Nanos2. Comparative matrix view of recombinase activities Alliance mouse Nanos2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nanos2 Mutation: 15 strains or lines available

References

• Original: J:305432 Webster NJ, et al., Testicular germ cell tumors arise in the absence of sex-specific differentiation. Development. 2021 May 1;148(9):dev197111
• All: 1 reference(s)