Nanos2^em1Jahe
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nanos2^em1Jahe
• Name: nanos C2HC-type zinc finger 2; endonuclease-mediated mutation 1, Jason Heaney
• MGI ID: MGI:6388704
• Synonyms: Nanos2^{em1(TagRFP)Jahe}, Nanos2^RFP
• Gene: Nanos2 Location: Chr7:18721449-18722887 bp, + strand Genetic Position: Chr7, 9.45 cM
• Alliance: Nanos2^em1Jahe page

Mutation origin

• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Endonuclease-mediated (No functional change, Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector introduced at the 3' end of the coding sequence a P2A sequence and TagRFP (a monomeric red/orange fluorescent protein generated from the wild-type RFP from sea anemone Entacmaea quadricolor) reporter gene. (J:305432)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nanos2 Mutation: 16 strains or lines available

References

• Original: J:305432 Webster NJ, et al., Testicular germ cell tumors arise in the absence of sex-specific differentiation. Development. 2021 May 1;148(9):dev197111
• All: 1 reference(s)