Folh1^tm2Jtc
Targeted Allele Detail

Summary

• Symbol: Folh1^tm2Jtc
• Name: folate hydrolase 1; targeted mutation 2, Joseph T Coyle
• MGI ID: MGI:6388547
• Synonyms: GCPII^-
• Gene: Folh1 Location: Chr7:86368185-86425151 bp, - strand Genetic Position: Chr7, 48.51 cM, cytoband D1-D2
• Alliance: Folh1^tm2Jtc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283436
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A PGK-neomycin selection cassette replacced a genomic fragment containing exons 9 and 10. (J:283436)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Folh1 Mutation: 50 strains or lines available

References

• Original: J:283436 Tsai G, et al., Early embryonic death of glutamate carboxypeptidase II (NAALADase) homozygous mutants. Synapse. 2003 Dec 15;50(4):285-92
• All: 1 reference(s)