Wdr62^tm1Jfch
Targeted Allele Detail

Summary

• Symbol: Wdr62^tm1Jfch
• Name: WD repeat domain 62; targeted mutation 1, Jian-Fu Chen
• MGI ID: MGI:6388422
• Synonyms: Wdr62^f
• Gene: Wdr62 Location: Chr7:29939563-29979844 bp, - strand Genetic Position: Chr7, 17.34 cM
• Alliance: Wdr62^tm1Jfch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282438
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 2 was replaced by a loxP-exon2-frt-neo-frt-loxP targeting vector via homologous recombination. (J:282438)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr62 Mutation: 47 strains or lines available

References

• Original: J:282438 Zhang W, et al., Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors. Nat Commun. 2019 Jun 13;10(1):2612
• All: 1 reference(s)