Opn5^em1(cre)Lan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Opn5^em1(cre)Lan
• Name: opsin 5; endonuclease-mediated mutation 1, Richard A Lang
• MGI ID: MGI:6387222
• Synonyms: Opn5^cre
• Gene: Opn5 Location: Chr17:42867674-42922286 bp, - strand Genetic Position: Chr17, 19.65 cM, cytoband B3
• Alliance: Opn5^em1(cre)Lan page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Opn5^em1(cre)Lan expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Opn5 (MGI:2662912)

• Mutation details: Using CRISPR/Cas9 technology, a cre recombinase cassette was targeted to be inserted into exon 1 of Opn5 gene. (J:279052)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Opn5 (mouse) Summary of all recombinase alleles driven by Opn5. Comparative matrix view of recombinase activities Alliance mouse Opn5 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Opn5 Mutation: 19 strains or lines available

References

• Original: J:279052 Nguyen MT, et al., An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye. Nat Cell Biol. 2019 Apr;21(4):420-429
• All: 3 reference(s)