Gt(ROSA)26Sor^{tm3(rtTA3)Yasu}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm3(rtTA3)Yasu}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Yasuhiro Yamada
• MGI ID: MGI:6386675
• Synonyms: Rosa26-stop-rtTA3-ires-Venus
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm3(rtTA3)Yasu} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279289
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Reporter, Transactivator)
• Mutation: Insertion
• Mutation details: A targeting vector consist of loxP-stop-loxP followed by reverse tetracycline transactivator 3 (rtTA3), IRES and a Venus reporter gene cassette into Gt(ROSA)26Sor gene was used to drive rtTA3 under control of endogenous Gt(ROSA026Sor promotor. (J:279289)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 944 strains or lines available

References

• Original: J:279289 Komura S, et al., Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas. Nat Commun. 2019 Sep 5;10(1):3999
• All: 1 reference(s)