Tppp3^tm1Yasu
Targeted Allele Detail

Summary

• Symbol: Tppp3^tm1Yasu
• Name: tubulin polymerization-promoting protein family member 3; targeted mutation 1, Yasuhiro Yamada
• MGI ID: MGI:6386669
• Synonyms: Tppp3-EGFP
• Gene: Tppp3 Location: Chr8:106194125-106198158 bp, - strand Genetic Position: Chr8, 53.04 cM, cytoband D1
• Alliance: Tppp3^tm1Yasu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279289
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector consist of IRES followed by EGFP-pA-rox-PGK-EM7-BsdR-pA-rox cassette into 3'-UTR of Tppp3 gene was used to drive EGFP under control of endogenous Tppp3 promotor. (J:279289)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tppp3 Mutation: 20 strains or lines available

References

• Original: J:279289 Komura S, et al., Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas. Nat Commun. 2019 Sep 5;10(1):3999
• All: 1 reference(s)