Tlr2tm1(cre)Dfil
Targeted Allele Detail
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Symbol: |
Tlr2tm1(cre)Dfil |
Name: |
toll-like receptor 2; targeted mutation 1, Dominik Filipp |
MGI ID: |
MGI:6385316 |
Synonyms: |
Tlr2Cre |
Gene: |
Tlr2 Location: Chr3:83743579-83749045 bp, - strand Genetic Position: Chr3, 37.4 cM
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Alliance: |
Tlr2tm1(cre)Dfil page
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Germline Transmission: |
Earliest citation of germline transmission:
J:281617
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Tlr2tm1(cre)Dfil expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The targeting vector is designed to insert Cre cassettes under the control of the Tlr2 promoter by BAC recombineering. After homologous recombination in ES cells, open reading frame of Tlr2 exon 3 was substituted with Cre.
(J:281617)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Tlr2
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tlr2 Mutation: |
56 strains or lines available
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Original: |
J:281617 Balounova J, et al., Toll-like receptor 2 expression on c-kit(+) cells tracks the emergence of embryonic definitive hematopoietic progenitors. Nat Commun. 2019 Nov 15;10(1):5176 |
All: |
1 reference(s) |
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