Mcoln3^tm1.2Jga
Targeted Allele Detail

Summary

• Symbol: Mcoln3^tm1.2Jga
• Name: mucolipin 3; targeted mutation 1.2, Jaime Garcia-Anoveros
• MGI ID: MGI:6383844
• Synonyms: Trpml3^Flox
• Gene: Mcoln3 Location: Chr3:145823205-145847561 bp, + strand Genetic Position: Chr3, 71.03 cM
• Alliance: Mcoln3^tm1.2Jga page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector was designed to insert a loxP site upstream of exon 7, and an FRT-flanked neomycin selection (neo) cassette followed by a second loxP site downstream of exon 8. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:187348)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mcoln3 Mutation: 36 strains or lines available

References

• Original: J:187348 Castiglioni AJ, et al., Expression and vesicular localization of mouse Trpml3 in stria vascularis, hair cells, and vomeronasal and olfactory receptor neurons. J Comp Neurol. 2011 Apr 15;519(6):1095-114
• All: 2 reference(s)