Hprt1^{tm1(CAG-iRFP)Bea}
Targeted Allele Detail

Summary

• Symbol: Hprt1^{tm1(CAG-iRFP)Bea}
• Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, The Beatson Institute for Cancer Research
• MGI ID: MGI:6382570
• Synonyms: Hprt^{tm1(CAG-LSL-iRFP)}, Hprt^{tm1(CAG-LSL-iRFP)Bea-3}, LSL-iRFP
• Gene: Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
• Alliance: Hprt1^{tm1(CAG-iRFP)Bea} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282268
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted upstream of the promoter a ubiquitous CAG promoter, floxed neomycin resistance cassette, iRFP reporter gene and polyadenylation sequence. (J:282268)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hprt1 Mutation: 1280 strains or lines available

References

• Original: J:282268 Hock AK, et al., Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo. Sci Rep. 2017 May 12;7(1):1837
• All: 2 reference(s)