Ormdl2^em1Rlp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ormdl2^em1Rlp
• Name: ORM1-like 2 (S. cerevisiae); endonuclease-mediated mutation 1, Richard L Proia
• MGI ID: MGI:6382067
• Gene: Ormdl2 Location: Chr10:128653771-128657498 bp, - strand Genetic Position: Chr10, 77.16 cM, cytoband D3
• Alliance: Ormdl2^em1Rlp page

Mutation origin

• Strain of Origin: C57BL/6NHsd

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing is used to introduce a 26 bp deletion, as well as a 1 bp insertion, in exon 2 of the gene. This mutation results in a frameshift and premature termination that eliminates more than 80% of the native protein coding sequence. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ormdl2 Mutation: 9 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)