Ripk3^tm2.1Geno
Targeted Allele Detail

Summary

• Symbol: Ripk3^tm2.1Geno
• Name: receptor-interacting serine-threonine kinase 3; targeted mutation 2.1, Genoway
• MGI ID: MGI:6380631
• Synonyms: Ripk3^FLAG
• Gene: Ripk3 Location: Chr14:56022452-56026314 bp, - strand Genetic Position: Chr14, 28.19 cM, cytoband C1
• Alliance: Ripk3^tm2.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279204
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutation: Insertion
• Mutation details: A 3x FLAG STOP replaced the endogenous stop codon. Cre-mediated recombination removed the loxP site flanked neomycin resistance gene cassette inserted into intron 9. (J:279204)

Expression

In Mice Carrying this Mutation:

31 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ripk3 Mutation: 31 strains or lines available

References

• Original: J:279204 Ferrando RE, et al., Immunohistochemical detection of FLAG-tagged endogenous proteins in knock-in mice. J Histochem Cytochem. 2015 Apr;63(4):244-55
• All: 1 reference(s)