C5ar2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: C5ar2^tm1Lex
• Name: complement component 5a receptor 2; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:6379036
• Synonyms: c5l2^-
• Gene: C5ar2 Location: Chr7:15968512-15978079 bp, - strand Genetic Position: Chr7, 8.77 cM
• Alliance: C5ar2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279795
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The entire coding region of the gene was replaced with a lacZ/neo cassette. (J:279795)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any C5ar2 Mutation: 20 strains or lines available

References

• Original: J:279795 Chen NJ, et al., C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a. Nature. 2007 Mar 8;446(7132):203-7
• All: 7 reference(s)